Gummerus A., Airaksinen M., Bengtström M. and Juppo A. Values and Disadvantages of Outsourcing the Regulatory Affairs Tasks in the Pharmaceutical Industry in EU Countries. Pharmaceutical Regulatory Affairs: Open Access Published date: April 15, 2016

Fontana F, Shahbazi MA, Liu D, Zhang H, Mäkilä E, Salonen J, Hirvonen J, Santos HA*, “Multistaged Nanovaccines based on Porous Silicon@Acetalated Dextran@Cancer Cell Membrane for Cancer Immunotherapy”, Adv. Mater. 2016. (accepted)

Mirza MU, Rafique S, Ali A, Munir M, Ikram N, Manan A, Salo-Ahen OMH, Idrees M. Towards peptide vaccines against Zika virus: Immunoinformatics combined with molecular dynamics simulations to predict antigenic epitopes of Zika viral proteins. Sci Rep. 2016 Dec 9;6:37313. doi: 10.1038/srep37313.

Elovaara H, Parkash V, Fair-Mäkelä R, Salo-Ahen OMH, Guedez G, Bligt-Lindén E, Grönholm J, Jalkanen S, Salminen TA. Multivalent Interactions of Human Primary Amine Oxidase with the V and C2 Domains of Sialic Acid-Binding Immunoglobulin-Like Lectin-9 Regulate Its Binding and Amine Oxidase Activity. PLoS One. 2016 Nov 28;11(11):e0166935. doi: 10.1371/journal.pone.0166935.

Herranz-Blanco B, Ginestar E, Zhang H, Hirvonen J, Santos HA*, “Microfluidics Platform for Glass Capillaries and its Application in Droplet and Nanoparticle Fabrication”, Int. J. Pharm. 2016. (accepted)

N. Prabhakar, J. Zhang*, D. Desai, E. Casals, T. Gulin-Sarfraz, T. Näreoja, J. Westermarck, J.M. Rosenholm*, Stimuli-responsive hybrid nanocarriers by controllable integration of hyperbranched PEI on mesoporous silica nanoparticles for sustained intracellular siRNA delivery. International Journal of Nanomedicine 2016, 11, 6591—6608.

N. Sandler & M. Preis. Printed Drug-Delivery Systems for Improved Patient Treatment. Trends in Pharmacological Sciences 2016. (In press)

H. Öblom, J. Berg, I. Alanko, M. Preis, N. Sandler, Thin substrates manufactured by means of 3D-printing for tailor-made drug delivery systems (EuPFI Special Issue, Abstract ID:7) International Journal of Pharmaceutics, 2016

T Suutari, T Silen, D Sen Karaman, H Saari, D Desai, E Kerkelä, S Laitinen, M Hanzlikova, J.M. Rosenholm, M Yliperttula, T Viitala, Real-time label-free monitoring of nanoparticle-cell interactions. Small 2016, DOI: 10.1002/smll.201601815

Skogman ME, Kanerva S, Manner S, Vuorela PM, Fallarero A. Flavones as Quorum Sensing Inhibitors Identified by a Newly Optimized Screening Platform Using Chromobacterium violaceum as Reporter Bacteria. Molecules. 2016 Sep 10;21(9). pii: E1211. doi: 10.3390/molecules21091211

S. Snipstad, S. Hak, H. Baghirov, E. Sulheim, Y. Mørch, S. Lelú, E. von Haartman, M. Bäck, K. Peter R. Nilsson, A. S. Klymchenko, C. de Lange Davies, A. K. O. Åslund: Labeling Nanoparticles: Dye Leakage and Altered Cellular Uptake Cytometria Part A 2016, DOI: 10.1002/cyto.a.22853

M. Preis, N. Sandler. Printing technologies and tailored dosing. Hospital Pharmacy Europe. 2016

H. Baghirov, D. Şen Karaman, T. Viitala, A. Duchanoy, Y.-R. Lou, V. Mamaeva, E. Pryazhnikov, L. Khiroug, C. de Lange Davies, C. Sahlgren, J.M. Rosenholm, Feasibility study of the permeability and uptake of mesoporous silica nanoparticles across the blood-brain barrier. PLOS One 2016, http://dx.doi.org/10.1371/journal.pone.016070

M. Preis, 'Arzneimittel aus dem Drucker – innovative Darreichungsformen in 2D und 3D' [Medicine out of the printer – innovative dosage forms in 2D and 3D] TechnoPharm 6 (4) 198-203 ( 2016).

D. Patra, D. Şen Karaman, D. Desai, E. El Khoury, J.M. Rosenholm, Preparation of curcumin loaded mesoporous silica nanoparticles: Determining polarizability inside the mesopores. Materials Research Bulletin 2016, 10.1016/j.materresbull.2016.08.012

H. Vakili, J.O. Nyman, N. Genina, M. Preis, N. Sandler, Application of a colorimetric technique in quality control for printed pediatric orodispersible drug delivery systems containing propranolol hydrochloride. Int. J. Pharmaceut. 511 (1), 2016, 606–618.

E. von Haartman, D. Lindberg, N. Prabhakar, J.M. Rosenholm, On the Intracellular Release Mechanism of Hydrophobic Cargo and its Relation to the Biodegradation Behavior of Mesoporous Silica Nanocarriers. European Journal of Pharmaceutical Sciences 2016, doi:10.1016/j.ejps.2016.06.001

V. Le Joncour, M. Hyvönen, E. Casals, P. Filppu, J. Tanjore Ramanathan, A. Ayo, J. Westermarck, J. Rosenholm, P. Laakkonen, Treating malignant glioma and brain metastasis with nanoparticles: Challenges of a peptide-based targeting and passage through the blood–brain-barrier. Eur. J. Cancer 2016 Vol. 61, Supp. 1, Page S19.

K. Lingeshwar Reddy, M. Rai, N. Prabhakar, S. Kumar Singh, S. Bahadur Rai, R. Arppe, J.M. Rosenholm* and V. Krishnan*, Controlled synthesis, bioimaging and toxicity assessments in strong red emitting Mn 2+ doped NaYF 4:Yb 3+/Ho 3+ nanophosphors. RSC Advances 2016 , 6, 53698 – 53704.

O.N. Pozharitskaya, M.V. Karlina, A.N. Shikov*, V.M. Kosman, V.G. Makarov, E. Casals, J.M. Rosenholm, Pharmacokinetics and Tissue Disposition of Nanosystem Entrapped Betulin  after Endotracheal Administration to Rats. European Journal of Drug Metabolism and Pharmacokinetics 2016 .

V.M. Paramonov , D. Desai, V. Mamaeva, J. Rosenholm, A. Rivero-Müller & C. Sahlgren, Mesoporous silica nanoparticles for somatostatin targeted Notch activation in animal model of pancreatic neuroendocrine cancer. 
Endocrine Abstracts (2016) 40 OC3 | DOI:10.1530/endoabs.40.OC3

D. Sen Karaman,* S. Sarwar, D. Desai, E.M. Björk, M. Odén, P. Chakrabarti, J.M. Rosenholm, S. Chakraborti,* Shape engineering boost antibacterial activity of mesoporous silica nanoparticles: A mechanistic investigation. Journal of Materials Chemistry B, 2016, 4, 3292-3304.

M. Palo, K. Kogermann, N. Genina, D. Fors, J. Peltonen, J. Heinämäki, N. Sandler, Quantification of caffeine and loperamide in printed formulations by infrared spectroscopy. Journal of Drug Delivery Science and Technology 2016.

V. Mamaeva, R. Niemi, M. Beck, E. Özliseli, D. Desai, S. Landor,  T. Gronroos, P. Kronqvist, I.K.N. Pettersen, E. McCormack, J.M. Rosenholm, M. Linden, C. Sahlgren, Inhibiting  Notch  activity  in  breast  cancer  stem  cells  by  glucose  functionalized nanoparticles carrying γ- secretase inhibitors. Molecular Therapy 2016, DOI: 10.1038/mt.2016.42

D. Şen Karaman, D. Desai, J. Zhang, S. Tadayon, G. Unal, J. Teuho, J. Sarfraz, J.-H. Smått, H. Gu, T. Näreoja, J.M. Rosenholm, Modulation of the structural properties of mesoporous silica nanoparticles to enhance the T1-weighted MR imaging capability. Journal of Materials Chemistry B, 2016, DOI: 10.1039/C5TB02371H

D. Desai, N. Prabhakar, V. Mamaeva, D. Șen Karaman, I.A.K. Lähdeniemi, C. Sahlgren, J.M. Rosenholm, D.M. Toivola, Targeted Modulation of Cell Differentiation in Distinct Regions of the Gastrointestinal Tract via Oral Administration of Differently PEI-PEG Functionalized Mesoporous Silica Nanoparticles. International Journal of Nanomedicine 11, 2016, 299—313.

J.M. Rosenholm,* T. Gulin-Sarfraz, V. Mamaeva, R. Niemi, E. Özliseli, D. Desai, D. Antfolk, E. von Haartman, D. Lindberg, N. Prabhakar, T. Näreoja, C. Sahlgren,* Prolonged dye release from mesoporous silica-based imaging probes facilitates long-term optical tracking of cell populations in vivo. Small 2016, doi: 10.1002/smll.201503392

E. Sulheim, H. Baghirov, E. von Haartman, A. Bøe, A.K.O. Åslund, Y. Mørch, C. de Lange Davies, Cellular uptake and intracellular degradation of poly(alkyl cyanoacrylate) nanoparticles. Journal of Nanobiotechnology 2016, 14:1 DOI: 10.1186/s12951-015-0156-7

J.M. Rosenholm, J. Zhang, M. Lindén, C. Sahlgren, Mesoporous silica nanoparticles in tissue engineering – a perspective (Review). Nanomedicine 2016, doi:10.2217/nnm.15.212

Holländer J, Genina N,  Jukarainen H, Khajeheian M., Rosling A.; Mäkilä E,  Sandler N. 3D printed PCL-based implantable prototypes of medical devices for controlled drug delivery,  J Pharm Sci. 2016, in press. doi: 10.1016/j.xphs.2015.12.012